In vitro activity of ceftaroline against a broad spectrum of recent clinical anaerobic isolates.
نویسندگان
چکیده
The in vitro activity of ceftaroline was compared with those of ceftriaxone, clindamycin, imipenem, metronidazole, moxifloxacin, tigecycline, and vancomycin against 514 clinical anaerobic isolates using Clinical and Laboratory Standards Institute (CLSI) standard methodology. Ceftaroline demonstrated good to excellent activity against Gram-positive anaerobic pathogens and limited activity against Gram-negative pathogens, particularly Bacteroides fragilis group isolates.
منابع مشابه
In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States.
This study evaluated the in vitro activity of ceftaroline, a novel cephalosporin with broad-spectrum activity against gram-negative and -positive pathogens, against 4,151 recent clinical isolates collected in the United States. Ceftaroline was very potent against bacteria found in community- and hospital-acquired infections, including methicillin-resistant Staphylococcus aureus, multidrug-resis...
متن کاملIn Vitro Antibacterial Activity of Rheum ribes Extract Obtained from Various Plant Parts Against Clinical Isolates of Gram-Negative Pathogens
Rheum ribes is among the Polygonaceae family which is endemic in Iran and a few neighboring countries. In this investigation, antibacterial effects of root, stalk and leaves extracts of Rheum ribes on a few common clinical isolates of gram negative pathogens were studied, using the cup plate and paper disc methods. Gram negative microorganisms studied were Escherichia coli, Klebsiella pneumonia...
متن کاملIn Vitro Antibacterial Activity of Rheum ribes Extract Obtained from Various Plant Parts Against Clinical Isolates of Gram-Negative Pathogens
Rheum ribes is among the Polygonaceae family which is endemic in Iran and a few neighboring countries. In this investigation, antibacterial effects of root, stalk and leaves extracts of Rheum ribes on a few common clinical isolates of gram negative pathogens were studied, using the cup plate and paper disc methods. Gram negative microorganisms studied were Escherichia coli, Klebsiella pneumonia...
متن کاملCeftaroline plus avibactam demonstrates bactericidal activity against pathogenic anaerobic bacteria in a one-compartment in vitro pharmacokinetic/pharmacodynamic model.
Anaerobic pathogens are often associated with polymicrobial infections, such as diabetic foot infections. Patients with these infections are often treated with broad-spectrum, multidrug therapies targeting resistant Gram-positive bacteria, such as methicillin-resistant Staphylococcus aureus, as well as Gram-negative bacteria and anaerobes. The broad-spectrum, non-beta-lactam, beta-lactamase inh...
متن کاملIn vitro evaluation of the antimicrobial activity of ceftaroline against cephalosporin-resistant isolates of Streptococcus pneumoniae.
Increasing pneumococcal resistance to extended-spectrum cephalosporins warrants the search for novel agents with activity against such resistant strains. Ceftaroline, a parenteral cephalosporin currently in phase 3 clinical development, has demonstrated potent in vitro activity against resistant gram-positive organisms, including penicillin-resistant Streptococcus pneumoniae. In this study, the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 55 1 شماره
صفحات -
تاریخ انتشار 2011